BDBM50613452 CHEMBL5269306

SMILES Cc1noc2CN=C(c3ccc(Cl)cc3)c3c(N)nccc3-c12

InChI Key InChIKey=IIRKIVCLTXICLY-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50613452   

TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50613452(CHEMBL5269306)
Affinity DataIC50:  90nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using biotinylated ligand incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50613452(CHEMBL5269306)
Affinity DataEC50:  720nMAssay Description:Inhibition of BRD4 BD1 in human Raji cells assessed as reduction of MYC RNA expression after 4 hrs by PCR analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed