BDBM506334 (1S,2R)-2-((R)-(1-((1-(4-((1-acryloylazetidin-3- yl)sulfonyl)phenyl)azetidin-3-yl)methyl)piperidin-4- yl)(cyano)(3-fluorophenyl)methyl)cyclopentyl methylcarbamate::US11045448, Cpd. No. 2

SMILES CNC(=O)O[C@H]1CCC[C@@H]1[C@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)C=C)CC1)c1cccc(F)c1

InChI Key InChIKey=YCHRNEMAHYDBHW-VLSLJKOQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506334   

TargetMenin(Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM506334((1S,2R)-2-((R)-(1-((1-(4-((1-acryloylazetidin-3- y...)
Affinity DataIC50:  374nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent