BDBM506357 US11045448, Cpd. No. 66::methyl ((1S,2R)-2-((S)-1-(1-((1-(4-((1-((E)-4- (dimethylamino)but-2-enoyl)azetidin-3-yl)sulfonyl)phenyl)-3- fluoroazetidin-3-yl)methyl)piperidin-4-yl)-2-(2-ethyl-1H- imidazol-1-yl)-1-(3-fluorophenyl)ethyl)cyclopentyl)carbamate

SMILES CCc1nccn1C[C@]([C@H]1CCC[C@@H]1NC(=O)OC)(C1CCN(CC2(F)CN(C2)c2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)\C=C\CN(C)C)CC1)c1cccc(F)c1

InChI Key InChIKey=BCTIJYSCGDNKEE-OKOZNKHASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506357   

TargetMenin(Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM506357(US11045448, Cpd. No. 66 | methyl ((1S,2R)-2-((S)-1...)
Affinity DataIC50:  1nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent