BDBM506362 US11045448, Cpd. No. 71::methyl ((1S,2R)-2-((S)-cyano(3-fluorophenyl)(1-((1-(4-((1- ((E)-4-(piperidin-1-yl)but-2-enoyl)azetidin-3- yl)sulfonyl)phenyl)azetidin-3-yl)methyl)piperidin-4- yl)methyl)cyclopentyl)carbamate

SMILES COC(=O)N[C@H]1CCC[C@@H]1[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)\C=C\CN2CCCCC2)CC1)c1cccc(F)c1

InChI Key InChIKey=UHUPMOFVAZPLBD-ZAOLGUQISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506362   

TargetMenin(Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM506362(US11045448, Cpd. No. 71 | methyl ((1S,2R)-2-((S)-c...)
Affinity DataIC50:  4nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent