BDBM506366 US11045448, Cpd. No. 75::methyl ((1S,2R)-2-((1S)-cyano((2R,6S)-1-((1-(4-((1-((E)-4- (dimethylamino)but-2-enoyl)azetidin-3- yl)sulfonyl)phenyl)azetidin-3-yl)methyl)-2,6- dimethylpiperidin-4-yl)(3- fluorophenyl)methyl)cyclopentyl)carbamate

SMILES COC(=O)N[C@H]1CCC[C@@H]1[C@@](C#N)(C1C[C@H](C)N(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)\C=C\CN(C)C)[C@H](C)C1)c1cccc(F)c1

InChI Key InChIKey=LDROCNQPOAZJPF-YDSZOHQPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506366   

TargetMenin(Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM506366(US11045448, Cpd. No. 75 | methyl ((1S,2R)-2-((1S)-...)
Affinity DataIC50:  6nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent