BDBM506864 3-amino-6-(5-(3-amino- 1,1,1-trifluoro-2-hydroxy- 3-oxopropan-2-yl)-2- methylphenyl)-N-((1r,4r)- 4-(2-hydroxypropan-2- yl)cyclohexyl)pyrazine-2- carboxamide trifluoroacetate::US11046658, Example 19
SMILES Cc1ccc(cc1-c1cnc(N)c(n1)C(=O)N[C@H]1CC[C@@H](CC1)C(C)(C)C)C(O)(C(N)=O)C(F)(F)F
InChI Key InChIKey=RVZOTMPIZFHEKY-GCDIYVDRSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 506864
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair