BDBM50745 3-(5,7-dimethoxy-2-oxidanylidene-4-phenyl-chromen-8-yl)-N,N-diethyl-3-(3,4,5-trimethoxyphenyl)propanamide::3-(5,7-dimethoxy-2-oxo-4-phenyl-1-benzopyran-8-yl)-N,N-diethyl-3-(3,4,5-trimethoxyphenyl)propanamide::3-(5,7-dimethoxy-2-oxo-4-phenylchromen-8-yl)-N,N-diethyl-3-(3,4,5-trimethoxyphenyl)propanamide::MLS000879482::N,N-diethyl-3-(2-keto-5,7-dimethoxy-4-phenyl-chromen-8-yl)-3-(3,4,5-trimethoxyphenyl)propionamide::SMR000465537::cid_16746297

SMILES CCN(CC)C(=O)CC(c1cc(OC)c(OC)c(OC)c1)c1c(OC)cc(OC)c2c(cc(=O)oc12)-c1ccccc1

InChI Key InChIKey=NSBWEIJFFUYGSD-UHFFFAOYSA-N

Data  2 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50745   

TargetELAV-like protein 1(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50745(3-(5,7-dimethoxy-2-oxidanylidene-4-phenyl-chromen-...)
Affinity DataKi:  590nMAssay Description:Inhibition of ELAV1 (unknown origin)-ARE sequence of Mushashi1 transcript complex formation after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetELAV-like protein 1(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50745(3-(5,7-dimethoxy-2-oxidanylidene-4-phenyl-chromen-...)
Affinity DataKi:  5.10E+3nMAssay Description:Inhibition of ELAV1 RRM1/RRM2 domains (unknown origin) interaction with ARE sequence of Mushashi1 transcript after 2 hrs by AlphaLISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 55(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50745(3-(5,7-dimethoxy-2-oxidanylidene-4-phenyl-chromen-...)
Affinity DataEC50:  1.31E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetELAV-like protein 1(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50745(3-(5,7-dimethoxy-2-oxidanylidene-4-phenyl-chromen-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of ELAV1 (unknown origin)-ARE sequence of Mushashi1 transcript complex formation after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50745(3-(5,7-dimethoxy-2-oxidanylidene-4-phenyl-chromen-...)
Affinity DataIC50:  5.26E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlycoprotein 42(Human herpesvirus 4 type 2)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50745(3-(5,7-dimethoxy-2-oxidanylidene-4-phenyl-chromen-...)
Affinity DataIC50:  5.40E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetELAV-like protein 1(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50745(3-(5,7-dimethoxy-2-oxidanylidene-4-phenyl-chromen-...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of ELAV1 RRM1/RRM2 domains (unknown origin) interaction with ARE sequence of Mushashi1 transcript after 2 hrs by AlphaLISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed