BDBM507687 N-((1R,4r)-4-(5-(6-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl)-4- (((1r,4R)-4-(5- (difluoromethyl)-1,3,4- oxadiazol-2-yl) cyclohexyl)amino)pyridin- 3-yl)-1,3,4-thiadiazol-2- yl)cy clohexyl)acetamide::US11046686, Example 2

SMILES CC(=O)NC1CC[C@@H](CC1)c1nnc(s1)-c1cnc(cc1N[C@H]1CCC(CC1)c1nnc(o1)C(F)F)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=YTFXUEGLENPSNF-KYDXEYDTSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 507687   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM507687(N-((1R,4r)-4-(5-(6-(3- cyanopyrrolo[1,2- b]pyridaz...)
Affinity DataIC50:  1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent