BDBM507771 7-chloro-1-(3-fluorophenyl)-4- (methylamino)quinazolin-2(1H)-one::US11046691, Compound 61::US11084798, Cpd No 61::US11130759, Cpd. No. 61

SMILES CNc1nc(=O)n(-c2cccc(F)c2)c2cc(Cl)ccc12

InChI Key InChIKey=IGCNCNQYVHDFQD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 507771   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM507771(7-chloro-1-(3-fluorophenyl)-4- (methylamino)quinaz...)
Affinity DataIC50: <200nMAssay Description:Materials:Enzyme: MAT2AhMAT2A: 50 nM, Cepter, 10 mg/mL (234 μM), amino acids 1-395Substrates: 500 uM eachReaction time: 1 hourL-methionine Subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent