BDBM508494 5-fluoro-N-[(8R,9aR)-8-hydroxy-5-oxo-8,9,9a,10-tetrahydro-5H,7H-pyrido[3,2-f]pyrrolo[2,1-c][1,4]oxazepin-3-yl]-2-(trifluoromethoxy)benzenesulfonamide::US11046710, Example 39

SMILES O[C@@H]1C[C@@H]2COc3ncc([N-]S(=O)(=O)c4cc(F)ccc4OC(F)(F)F)cc3C(=O)N2C1

InChI Key InChIKey=RDWOHSHQYGQUDI-VXGBXAGGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508494   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM508494(5-fluoro-N-[(8R,9aR)-8-hydroxy-5-oxo-8,9,9a,10-tet...)
Affinity DataIC50:  2.40nMAssay Description:COS1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (Inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent