BDBM508515 N-(2-(5-(3,4-dichlorophenyl)furan-2-yl)ethyl)-3-(morpholine-4-carbonyl)-1H-pyrazole-5-carboxamide::US11046713, Example 8

SMILES Clc1cccc(-c2ccc(CNC(=O)c3cc(n[nH]3)C(=O)N3CCOCC3)o2)c1Cl

InChI Key InChIKey=PQTDIJRJKUNEIQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 508515   

TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM508515(N-(2-(5-(3,4-dichlorophenyl)furan-2-yl)ethyl)-3-(m...)
Affinity DataKi:  62nMAssay Description:Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM508515(N-(2-(5-(3,4-dichlorophenyl)furan-2-yl)ethyl)-3-(m...)
Affinity DataIC50:  606nMAssay Description:Antagonism of test compounds for AR was measured by reporter gene assay in human embryonic kidney (HEK293) cells stably transfected with an expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent