BDBM508542 8-[2-(3-cyclopropyl-3- fluoroazetidin-1-yl)ethyl]-2,2- difluoro[1,3]dioxolo[4,5- h][1,2,4]triazolo[1,5- c]quinazolin-5-amine::US11046714, Example 18

SMILES Nc1nc2c3OC(F)(F)Oc3ccc2c2nc(CCN3CC(F)(C3)C3CC3)nn12

InChI Key InChIKey=JRTHLTIYKPPTEH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508542   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508542(8-[2-(3-cyclopropyl-3- fluoroazetidin-1-yl)ethyl]-...)
Affinity DataKi:  1.60nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent