BDBM508547 2,2-difluoro-8-{2-[(2R,4S)-4- fluoro-2-methylpyrrolidin-1- yl]ethyl}[1,3]dioxolo[4,5- h][1,2,4]triazolo[1,5- c]quinazolin-5-amine::US11046714, Example 22

SMILES C[C@@H]1C[C@H](F)CN1CCc1nc2c3ccc4OC(F)(F)Oc4c3nc(N)n2n1

InChI Key InChIKey=ABVUYCPJEBHHQX-BDAKNGLRSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508547   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508547(2,2-difluoro-8-{2-[(2R,4S)-4- fluoro-2-methylpyrro...)
Affinity DataKi:  1.5nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent