BDBM508587 2,2-difluoro-8-{2-[(2R)-2- methyl-4-(2-methyl-1,3-thiazol- 5-yl)piperazin-1-yl]ethyl} [1,3]dioxolo[4,5-h][1,2,4] triazolo[1,5-c]quinazolin-5- amine::US11046714, Example 45

SMILES C[C@@H]1CN(CCN1CCc1nc2c3ccc4OC(F)(F)Oc4c3nc(N)n2n1)c1cnc(C)s1

InChI Key InChIKey=FHKCSNKDZARFSL-LLVKDONJSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508587   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508587(2,2-difluoro-8-{2-[(2R)-2- methyl-4-(2-methyl-1,3-...)
Affinity DataKi:  1.5nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent