BDBM508636 8-[(2R)-2-(5,8-dihydro-1,7- naphthyridin-7(6H)-yl)propyl]- 2,2-difluoro[1,3]dioxolo[4,5-h] [1,2,4]triazolo[1,5-c]quinazolin- 5-amine::US11046714, Example 78

SMILES C[C@H](Cc1nc2c3ccc4OC(F)(F)Oc4c3nc(N)n2n1)N1CCc2cccnc2C1

InChI Key InChIKey=LLLIUSFZCVTVMI-LLVKDONJSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508636   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508636(8-[(2R)-2-(5,8-dihydro-1,7- naphthyridin-7(6H)-yl)...)
Affinity DataKi:  1.40nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent