BDBM508669 2,2-difluoro-8-{[(2R)-4-(4- fluorophenyl)-2-methylpiperazin-1- yl]methyl}[1,3]dioxolo[4,5-h][1,2,4] triazolo[1,5-c]quinazolin-5-amine::US11046714, Example 106

SMILES C[C@@H]1CN(CCN1Cc1nc2c3ccc4OC(F)(F)Oc4c3nc(N)n2n1)c1ccc(F)cc1

InChI Key InChIKey=LBNQCEQRHYQKFU-GFCCVEGCSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508669   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508669(2,2-difluoro-8-{[(2R)-4-(4- fluorophenyl)-2-methyl...)
Affinity DataKi:  2.10nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent