BDBM509155 Compound 1-57::US11072585, Example 52::US11072585, Example 99

SMILES CC(C)(C)OC(=O)N1CCN(CC1)C(=O)Cn1ccc2c(Oc3cc(CN)cc(n3)C(F)(F)F)cccc12

InChI Key InChIKey=HONNWTDYWUAZJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 509155   

TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM509155(Compound 1-57 | US11072585, Example 52 | US1107258...)
Affinity DataIC50:  650nMAssay Description:LOXL2 amine oxidase activity is evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells stably expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

US Patent
LigandPNGBDBM509155(Compound 1-57 | US11072585, Example 52 | US1107258...)
Affinity DataIC50: <300nMAssay Description:LOXL2 amine oxidase activity is evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells stably expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent