BDBM509682 US11364246, Example 30.4::US20200361871A1, Example 30.4

SMILES CC12CC(C1)(C2)NC(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccn1

InChI Key InChIKey=IXDHDQWNUZFWAH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 509682   

TargetAnoctamin-1(Homo sapiens (Human))
Tmem16A

US Patent
LigandPNGBDBM509682(US11364246, Example 30.4 | US20200361871A1, Exampl...)
Affinity DataEC50:  750nMAssay Description:Cell Culture and PreparationFisher rat thyroid (FRT) cells stably expressing human TMEM16A (TMEM16Aabc variant; Dr Luis Galietta, Insituto Giannina, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-1(Homo sapiens (Human))
Tmem16A

US Patent
LigandPNGBDBM509682(US11364246, Example 30.4 | US20200361871A1, Exampl...)
Affinity DataEC50:  750nMAssay Description:Compound activity was quantified by measuring the increase in current upon compound addition and expressing this as a percentage increase of baseline...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent