BDBM510076 US11351149, Example 28::WO2021250648, Example 28

SMILES CC(C)(C)C[C@H](NC(=O)COC1CCCCC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N

InChI Key InChIKey=XOZLJIRPICWZCP-BQFCYCMXSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 510076   

TargetReplicase polyprotein 1a(2019-nCoV)
Pfizer

US Patent
LigandPNGBDBM510076(US11351149, Example 28 | WO2021250648, Example 28)
Affinity DataKi:  1.79E+3nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510076(US11351149, Example 28 | WO2021250648, Example 28)
Affinity DataIC50:  1.79E+3nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510076(US11351149, Example 28 | WO2021250648, Example 28)
Affinity DataEC50:  7.26E+3nMAssay Description:The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed