BDBM510125 3-Methyl-N-(trifluoroacetyl)-L-valyl-(4R)-N-{(1 S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl] ethyl}-4-(trifluoromethyl)-L-prolinamide (77)::WO2021250648, Example 77

SMILES CC(C)(C)C(NC(=O)C(F)(F)F)C(=O)N1CC(C[C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N)C(F)(F)F

InChI Key InChIKey=XQTPLFBEESJXJI-NBWCBLLSSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510125   

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510125(3-Methyl-N-(trifluoroacetyl)-L-valyl-(4R)-N-{(1 S)...)
Affinity DataEC50:  85nMAssay Description:The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510125(3-Methyl-N-(trifluoroacetyl)-L-valyl-(4R)-N-{(1 S)...)
Affinity DataIC50:  4nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed