BDBM510546 N-tert-Butyl-5-[3-methyl-3-(pyridin-2-yl)azetidine-1-carbonyl]pyridin-2-amine::US11078182, Ex. 8

SMILES CC(C)(C)Nc1ccc(cn1)C(=O)N1CC(C)(C1)c1ccccn1

InChI Key InChIKey=ASBJFLGCEWFOAZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 510546   

TargetPantetheinase [22-493](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM510546(N-tert-Butyl-5-[3-methyl-3-(pyridin-2-yl)azetidine...)
Affinity DataIC50:  0.300nMAssay Description:0.1 nM of FLAG-tagged Vanin-1 (AA 22-493, T26I, produced internally) and test compounds are incubated at room temperature for 20 minutes in assay buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPantetheinase(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM510546(N-tert-Butyl-5-[3-methyl-3-(pyridin-2-yl)azetidine...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human vanin-1 in whole bloodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPantetheinase(Homo sapiens (Human))
Lauren Mccallister

Curated by ChEMBL
LigandPNGBDBM510546(N-tert-Butyl-5-[3-methyl-3-(pyridin-2-yl)azetidine...)
Affinity DataIC50:  300nMAssay Description:Inhibition of vanin-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed