BDBM510690 US11078186, Example 144
SMILES C[C@]1(CN(C[C@@H]1c1ccccc1)C(=O)NCc1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F
InChI Key InChIKey=XBTSCCZZJWSYDU-NOZRDPDXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 510690
Affinity DataIC50: 463nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 877nMAssay Description:Inverse agonist activity at RORgammat (unknown origin) expressed in Jurkat cells by reporter assayMore data for this Ligand-Target Pair