BDBM511435 (-)-(1R,5S)-2-[5-(2,5-Difluoro-phenylethynyl)-pyridin-2-yl]-4-methyl-2,4-diazabicyclo[3.2.0]heptan-3-one::US11059766, Example 4

SMILES CN1[C@H]2CC[C@H]2N(C1=O)c1ccc(cn1)C#Cc1cc(F)ccc1F

InChI Key InChIKey=VPJZBZSJQDZUQZ-DLBZAZTESA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511435   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM511435((-)-(1R,5S)-2-[5-(2,5-Difluoro-phenylethynyl)-pyri...)
Affinity DataKi:  3nMAssay Description:For binding experiments, cDNA encoding human mGlu5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM511435((-)-(1R,5S)-2-[5-(2,5-Difluoro-phenylethynyl)-pyri...)
Affinity DataEC50:  3nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent