BDBM511556 US11059794, Example 6.16::tert-butyl 4-[2-(2-fluoro-4- sulfamoylphenyl)sulfinylethyl]- piperidine-1-carboxylate (intermediate 10.4)/3-[2-[(5- methyltetrazol-2-yl)methyl]-4- (trifluoromethyl)phenyl]propanoic acid (CAS-RN 1646783-83-6)

SMILES Cc1nnn(Cc2cc(ccc2CCC(=O)N2CCC(CCS(=O)c3ccc(cc3F)S(N)(=O)=O)CC2)C(F)(F)F)n1

InChI Key InChIKey=DFDVFDLIWVLQIA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511556   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM511556(US11059794, Example 6.16 | tert-butyl 4-[2-(2-fluo...)
Affinity DataIC50:  12.3nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM511556(US11059794, Example 6.16 | tert-butyl 4-[2-(2-fluo...)
Affinity DataIC50:  4nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent