BDBM511626 US11059801, Compound dBET34
SMILES Cc1cnc(Nc2ccc(cc2)N2CCN(CC2)C(=O)CCC(=O)NCCCOCCOCCOCCCNC(=O)COc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C
InChI Key InChIKey=RDUUOZOVVAJAKF-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 511626
TargetBromodomain-containing protein 4 [49-170]/DNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Dana-Farber Cancer Institute
US Patent
Affinity DataIC50: 1.54E+3nMAssay Description:AlphaScreen technology was used to detect CRBN-DDB1/BRD4 dimerization induced by dBET molecules. In brief, GST-BRD4[49-170] (Sigma Aldrich) and CRBN-...More data for this Ligand-Target Pair