BDBM513484 4-(3,3-diethyl-7-fluoro-2-methyl-3H-indol-5-yl)-5-fluoro-N-(5-(1-methylpiperidin-4-yl)pyridin-2-yl)pyrimidine-2-amino::US11091476, Example 38

SMILES CCC1(CC)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)C2CCN(C)CC2)ncc1F

InChI Key InChIKey=NQZLCGLQVAVSGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 513484   

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM513484(4-(3,3-diethyl-7-fluoro-2-methyl-3H-indol-5-yl)-5-...)
Affinity DataIC50:  0.200nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase/G1/S-specific cyclin- 2(Homo sapiens (Human))
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM513484(4-(3,3-diethyl-7-fluoro-2-methyl-3H-indol-5-yl)-5-...)
Affinity DataIC50:  19.8nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent