BDBM513485 1-(2-((4-(3-Ethyl-7-fluoro-2,3-dimethyl-3H-indol-5-yl)-5-fluoropyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridine-6 (5H)-yl)-2-hydroxyacetamide::US11091476, Example 39

SMILES CCC1(C)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc3CN(CCc3n2)C(=O)CO)ncc1F

InChI Key InChIKey=UMJDAZSXABEMLH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 513485   

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM513485(1-(2-((4-(3-Ethyl-7-fluoro-2,3-dimethyl-3H-indol-5...)
Affinity DataIC50:  5.65nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase/G1/S-specific cyclin- 2(Homo sapiens (Human))
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM513485(1-(2-((4-(3-Ethyl-7-fluoro-2,3-dimethyl-3H-indol-5...)
Affinity DataIC50:  38.5nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent