BDBM513486 1-(2-((5-fluoro-4-(7′-fluoro-2′-methylspiro[cyclopentane-1,3′-indol]-5′-yl) pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridine-6 (5H)-yl)-2-hydroxyacetamide::US11091476, Example 40

SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc4CN(CCc4n3)C(=O)CO)ncc2F)C11CCCC1

InChI Key InChIKey=VAWYHOYAWTUTHR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 513486   

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM513486(1-(2-((5-fluoro-4-(7′-fluoro-2′-methyl...)
Affinity DataIC50:  25nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase/G1/S-specific cyclin- 2(Homo sapiens (Human))
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM513486(1-(2-((5-fluoro-4-(7′-fluoro-2′-methyl...)
Affinity DataIC50:  162nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent