BDBM514530 US11096924, DASH-inhibitors 4949::US11583516, Cmpd ID 4949

SMILES N[C@H](C(=O)N1CCC[C@H]1B(O)O)C1(CC1)C(F)(F)F

InChI Key InChIKey=DUQWZJWFTUCARE-NKWVEPMBSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 514530   

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  2.40E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial (PREP)(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  58nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  2.20E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  3.90E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  1.20E+6nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHomeobox protein PKNOX1(Human)
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  5.80E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  24nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  19nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  22nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  39nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  1.20E+3nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  58nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  24nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  19nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  22nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  39nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  1.20E+3nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM514530(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)
Affinity DataIC50:  1.90E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent