BDBM514549 6,6-dimethyl-8-(6- (trifluoromethyl)imidazo[1,5- a]pyridin-8-yl)-1,3,8- triazaspiro[4.5]decane-2,4- dione::US11096930, Example 12
SMILES CC1(C)CN(CCC11NC(=O)NC1=O)c1cc(cn2cncc12)C(F)(F)F
InChI Key InChIKey=ZOTCSZPLMLFDHA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 514549
Affinity DataIC50: 794nMAssay Description:Recombinant human IDO or TDO was incubated in 50 mM KPO4 (pH 7.0), 0.5 mM EGTA, 0.5 mM EDTA, 0.05% Triton™ X100, 20 mM ascorbate, 10 μM methylen...More data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+3nMAssay Description:Recombinant human IDO or TDO was incubated in 50 mM KPO4 (pH 7.0), 0.5 mM EGTA, 0.5 mM EDTA, 0.05% Triton™ X100, 20 mM ascorbate, 10 μM methylen...More data for this Ligand-Target Pair