BDBM514557 6,6-dimethyl-3-((tetrahydro- 2H-pyran-4-yl)methyl)-8-(7- (trifluoromethyl)imidazo[1,5- a]pyridin-5-yl)-1,3,8- triazaspiro[4.5]decane-2,4- dione::US11096930, Example 14
SMILES CC1(C)CN(CCC11NC(=O)N(CC2CCOCC2)C1=O)c1cc(cc2cncn12)C(F)(F)F
InChI Key InChIKey=PECZITWUDKRWTR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 514557
Affinity DataIC50: 1.66E+4nMAssay Description:Recombinant human IDO or TDO was incubated in 50 mM KPO4 (pH 7.0), 0.5 mM EGTA, 0.5 mM EDTA, 0.05% Triton™ X100, 20 mM ascorbate, 10 μM methylen...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Recombinant human IDO or TDO was incubated in 50 mM KPO4 (pH 7.0), 0.5 mM EGTA, 0.5 mM EDTA, 0.05% Triton™ X100, 20 mM ascorbate, 10 μM methylen...More data for this Ligand-Target Pair