BDBM514561 2-methyl-8-(7- (trifluoromethyl)imidazo[1,5- a]pyridin-5-yl)-1,3,8- triazaspiro[4.5]dec-1-en-4-one::US11096930, Example 18

SMILES CC1=NC2(CCN(CC2)c2cc(cc3cncn23)C(F)(F)F)C(=O)N1

InChI Key InChIKey=IUDDWDTZLDXFQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 514561   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM514561(2-methyl-8-(7- (trifluoromethyl)imidazo[1,5- a]pyr...)
Affinity DataIC50:  2.00E+3nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent