BDBM514716 (S)-N-(3-(2-(2,5-dihydrofuran-3-yl)-6- (((R)-1-hydroxypropan-2- yl)amino)pyridin-4-yl)-4-methylphenyl)- 3-(2,2,2-trifluoroethyl)pyrrolidine-1- carboxamide::US11098031, Example 78
SMILES C[C@H](CO)Nc1cc(cc(n1)C1=CCOC1)-c1cc(NC(=O)N2CC[C@@H](CC(F)(F)F)C2)ccc1C
InChI Key InChIKey=WFXADWBZLIDHEL-MSOLQXFVSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 514716
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Kinnate Biopharma
US Patent
Kinnate Biopharma
US Patent
Affinity DataIC50: <10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair