BDBM514721 (S)-N-(3-(2'-cyano-6-(((R)-1- hydroxypropan-2-yl)amino)-[2,4'- bipyridin]-4-yl)-4-methylphenyl)-3- (2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide::US11098031, Example 83
SMILES C[C@H](CO)Nc1cc(cc(n1)-c1ccnc(c1)C#N)-c1cc(NC(=O)N2CC[C@@H](CC(F)(F)F)C2)ccc1C
InChI Key InChIKey=IFRZZOVTXFMHBK-MOPGFXCFSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 514721
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Kinnate Biopharma
US Patent
Kinnate Biopharma
US Patent
Affinity DataIC50: <10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair