BDBM514734 (S)-N-(3-(6-((2-hydroxy-2- methylpropyl)amino)-2- morpholinopyrimidin-4-yl)-4- methylphenyl)-3-(2,2,2- trifluoroethyl)pyrrolidine-1-carboxamide::US11098031, Example 96
SMILES Cc1ccc(NC(=O)N2CC[C@@H](CC(F)(F)F)C2)cc1-c1cc(NCC(C)(C)O)nc(n1)N1CCOCC1
InChI Key InChIKey=KOPFLORRAHJDJO-SFHVURJKSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 514734
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Kinnate Biopharma
US Patent
Kinnate Biopharma
US Patent
Affinity DataIC50: <10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair