BDBM514754 (3S)-N-(3-[2-[(5R)-5-hydroxy-2- oxopiperidin-1-yl]-6-(morpholin-4- yl)pyridin-4-yl]-4-methylphenyl)-3- (2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide::US11098031, Example 116
SMILES Cc1ccc(NC(=O)N2CC[C@@H](CC(F)(F)F)C2)cc1-c1cc(nc(c1)N1CC(O)CCC1=O)N1CCOCC1
InChI Key InChIKey=WAGHLZVNPIEZCN-YDNXMHBPSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 514754
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Kinnate Biopharma
US Patent
Kinnate Biopharma
US Patent
Affinity DataIC50: <10nMAssay Description:Small molecule inhibition of RAF1 kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase and ...More data for this Ligand-Target Pair