BDBM515513 (3-Chloro-6-methoxypyridin-2-yl)(3-{[2-(4-isopropylphenyl)imidazo[1,2-a]pyrimidin-3-yl]methyl}-3,8-diazabicyclo[3.2.1]oct-8-yl)methanone::US11098063, Example 29

SMILES COc1ccc(Cl)c(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(cc1)C(C)C)C2

InChI Key InChIKey=VDKJCAWGDJJKNL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 515513   

TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM515513((3-Chloro-6-methoxypyridin-2-yl)(3-{[2-(4-isopropy...)
Affinity DataIC50:  21nMAssay Description:Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM515513((3-Chloro-6-methoxypyridin-2-yl)(3-{[2-(4-isopropy...)
Affinity DataIC50:  1.80nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM515513((3-Chloro-6-methoxypyridin-2-yl)(3-{[2-(4-isopropy...)
Affinity DataIC50:  280nMAssay Description:Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM515513((3-Chloro-6-methoxypyridin-2-yl)(3-{[2-(4-isopropy...)
Affinity DataIC50:  42.7nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent