BDBM515526 (7-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-yl]methyl}-3-oxa-7,9-diazabicyclo[3.3.1]non-9-yl)[6-(methylsulfanyl)pyridin-2-yl]methanone::US11098063, Example 16

SMILES CSc1cccc(n1)C(=O)N1C2COCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2

InChI Key InChIKey=PUSPHEWNSUMZGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 515526   

TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
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US Patent
LigandPNGBDBM515526((7-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-y...)
Affinity DataIC50:  12nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
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US Patent
LigandPNGBDBM515526((7-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-y...)
Affinity DataIC50:  670nMAssay Description:Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent