BDBM515810 US11053225, Compound 201

SMILES OCCn1cc(cn1)-c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1Nc1ccc(cc1)C1CCNCC1

InChI Key InChIKey=FTUDPMMKHAMLKT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 515810   

TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515810(US11053225, Compound 201)
Affinity DataIC50:  0.0120nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515810(US11053225, Compound 201)
Affinity DataIC50:  850nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515810(US11053225, Compound 201)
Affinity DataIC50:  150nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent