BDBM515831 US11053225, Compound 132

SMILES Clc1cc(Cl)cc(Nc2ncc(-c3cnn(c3)C3CCNCC3)c(Nc3ccc4CCNCc4c3)n2)c1

InChI Key InChIKey=FBBJSCGMJHFVOD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 515831   

TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515831(US11053225, Compound 132)
Affinity DataIC50:  0.200nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515831(US11053225, Compound 132)
Affinity DataIC50:  4.90nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515831(US11053225, Compound 132)
Affinity DataIC50:  270nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent