BDBM516581 7-(4-(((R)-1-cyanoethyl)amino)-5-(1-((R)-2-fluoro-3-hydroxy-3-methylbutyl)-1H-1,2,3-triazol-4-yl)pyridin-2-yl)pyrrolo[1,2-b]pyridazine-3-carbonitrile::US11053250, Compound 1

SMILES C[C@@H](Nc1cc(ncc1-c1cn(C[C@@H](F)C(C)(C)O)nn1)-c1ccc2cc(cnn12)C#N)C#N

InChI Key InChIKey=LBQSAAKBPQVFHG-JLCFBVMHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516581   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM516581(7-(4-(((R)-1-cyanoethyl)amino)-5-(1-((R)-2-fluoro-...)
Affinity DataIC50: <1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent