BDBM516840 US11104664, Compound P-12

SMILES CCN(C1CCN(CC(F)(F)F)CC1)c1c(C)c(cc2nn(C)cc12)C(=O)NCc1c(OC)cc(C)[nH]c1=O

InChI Key InChIKey=LKVKXYXKESABSQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516840   

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM516840(US11104664, Compound P-12)
Affinity DataIC50:  117nMAssay Description:Recombinant PRC2 (EZH2-Y641F) was purchased from Active motif, S-adenosyl-methionine (SAM) and Poly-L-lysine (PLL) were purchased from Sigma-Aldrich,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent