BDBM516848 US11104664, Compound P-19
SMILES CCN([C@H]1CC[C@@H](CC1)N1CC(C1)OC)c1c(CC)c(cc2n(C)ncc12)C(=O)NCc1c(C)cc(C)[nH]c1=O
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 516848
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Recombinant PRC2 (EZH2-Y641F) was purchased from Active motif, S-adenosyl-methionine (SAM) and Poly-L-lysine (PLL) were purchased from Sigma-Aldrich,...More data for this Ligand-Target Pair