BDBM516879 US11104664, Compound D4

SMILES CN(C1CCC(CC1)NC(F)(F)F)c1cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c(C)c2n(C)ncc12

InChI Key InChIKey=ZQYSNKZISLBGFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516879   

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM516879(US11104664, Compound D4)
Affinity DataIC50: >1.00E+4nMAssay Description:Recombinant PRC2 (EZH2-Y641F) was purchased from Active motif, S-adenosyl-methionine (SAM) and Poly-L-lysine (PLL) were purchased from Sigma-Aldrich,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent