BDBM517839 Preparation of N-(4-(difluoromethoxy)-2-((2-(dimethylaminoethyl)(methyl)amino)-5-((4-(4-fluoro-1-iso propyl-2-methyl-1H-benzo[d]imidazole6-yl)pyrimidin-2-yl)amino)phenyl)acrylamide::US11111233, Example 47

SMILES CC(C)n1c(C)nc2c(F)cc(cc12)-c1ccnc(Nc2cc(NC(=O)C=C)c(cc2OC(F)F)N(C)CCN(C)C)n1

InChI Key InChIKey=TUQMZMRLHJMFME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 517839   

TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM517839(Preparation of N-(4-(difluoromethoxy)-2-((2-(dimet...)
Affinity DataIC50: <1nMAssay Description:Reagents and Materials:WT EGFR (Carna, Cat. No. 08-115), EGFR [L858R] (Carna, Cat. No. 08-502), EGFR [L858R/T790M] (Carna, Cat. No. 08-510), ATP (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM517839(Preparation of N-(4-(difluoromethoxy)-2-((2-(dimet...)
Affinity DataIC50:  25nMAssay Description:Reagents and Materials:WT EGFR (Carna, Cat. No. 08-115), EGFR [L858R] (Carna, Cat. No. 08-502), EGFR [L858R/T790M] (Carna, Cat. No. 08-510), ATP (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent