BDBM517846 US11111233, Example 54

SMILES COc1cc(ccc1Nc1nccc(n1)-c1cc(F)c2nc(C)n(C(C)C)c2c1)N1CCN(C)CC1

InChI Key InChIKey=VYGCBAWMDOWVPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 517846   

TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM517846(US11111233, Example 54)
Affinity DataIC50: <1nMAssay Description:Reagents and Materials:WT EGFR (Carna, Cat. No. 08-115), EGFR [L858R] (Carna, Cat. No. 08-502), EGFR [L858R/T790M] (Carna, Cat. No. 08-510), ATP (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM517846(US11111233, Example 54)
Affinity DataIC50:  25nMAssay Description:Reagents and Materials:WT EGFR (Carna, Cat. No. 08-115), EGFR [L858R] (Carna, Cat. No. 08-502), EGFR [L858R/T790M] (Carna, Cat. No. 08-510), ATP (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent