BDBM518420 (2S,3R)-2-Methyl-1-[4-[1-[(3R)- pyrrolidin-3-yl]pyrazol-4-yl]-6- (trifluoromethyl)pyrimidin-2- yl]azetidin-3-ol::US11124500, Example 14
SMILES C[C@H]1[C@H](O)CN1c1nc(cc(n1)C(F)(F)F)-c1cnn(c1)[C@@H]1CCNC1
InChI Key InChIKey=LGEBDZHNMFGOOZ-UFGOTCBOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 518420
Affinity DataIC50: 19.1nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
Affinity DataIC50: 15.9nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair