BDBM519993 4-(3-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(methoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)-3-oxohexahydroimidazo[1,5-a]pyrazin-2(3H)-yl)-5-fluorophenoxy)cyclohexane carboxylic acid::US11142527, Example 23

SMILES COC(=O)C1=C(CN2CCN3[C@H](CN(C3=O)c3cc(F)cc(OC4CCC(CC4)C(O)=O)c3)C2)NC(=N[C@H]1c1ccc(F)cc1Cl)c1nccs1

InChI Key InChIKey=JNDRCYGKJPGIJC-REFRKFAXSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519993   

TargetLarge envelope protein(Hepatitis B virus)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM519993(4-(3-((S)-7-(((R)-6-(2-chloro-4-fluorophenyl)-5-(m...)
Affinity DataEC50:  7nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent