BDBM521842 US11155546, Compound G-9

SMILES COCCOc1ccc(Nc2nc(NC3CCN(C3)C(=O)C=C)c(F)c3CNC(=O)c23)cc1

InChI Key InChIKey=IOJJFGHOUPJKDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521842   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology

US Patent
LigandPNGBDBM521842(US11155546, Compound G-9)
Affinity DataIC50:  1.01E+3nMAssay Description:EGFR: The working concentration of each component in 10 μl wild-type EGFR kinase reaction system was: 10 μM ATP, 0.8 ng/μl wild-type E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology

US Patent
LigandPNGBDBM521842(US11155546, Compound G-9)
Affinity DataIC50:  7nMAssay Description:BTK: The compound was predissolved in 100% DMSO. 10 mM drug stock solution was obtained by dissolution at room temperature and then serially diluted ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent