BDBM522392 8-chloro-2-(4,4-difluorocyclohexyl)-1-[(2R,4R)-2-methyltetrahydro-2H-pyran-4-yl]-1H-imidazo[-c]quinoline::US11161844, Example 8
SMILES C[C@@H]1CC(CCO1)n1c(nc2cnc3ccc(Cl)cc3c12)C1CCC(F)(F)CC1
InChI Key InChIKey=FMJXDKFGYNPFHX-JBZHPUCOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 522392
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 12.1nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
Affinity DataIC50: 15.9nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair